INTRODUCTION
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The chemical 'cathinone' is a stimulant drug which occurs naturally in the plant called Khat. Synthetic cathinones are β-keto phenethylamines and chemically they are similar to amphetamine and methamphetamine. Synthetically produced chemicals such as mephedrone, methylone (M1) and MDPV – all fall under the cathinones chemical group. The principal active ingredient found in the leaves of the khat plant (catha edulis) is used for synthesizing a range of synthetic cathinones.
cathinone - gr8researchchemicals-eu.com
Chemical formula: C9H11NO
Molar Mass: 149.19g/mol
Chemical Name: (S)-2-Amino-1-phenyl-1-propanone
Common Name: Bath Salts
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HISTORY
Synthetic cathinones appeared in the drug market in the mid-2000s. Methylone was the first synthetic cathinone reported to the European Monitoring Centre on Drugs and Drug Addiction (EMCDDA) in 2005. In 2007, reports of mephedrone use emerged different countries and regions. It was then declared illegal to use for recreation purpose in some countries around the world.
MECHANISM OF ACTION
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Cathinone stimulates the release of dopamine and inhibit the re-uptake of neurotransmitters in the Central Nervous System (CNS). Since cathinone is a hydrophobic molecule, it can easily cross cell membranes and even the blood brain barrier. That’s why cathinone interacts with the monoamine transporters present in neurons. Cathinone also induces the release of dopamine from brain striatal preparations. This chemical can also affect the Peripheral Nervous System (PNS). It blocks adrenergic receptors and inhibits smooth muscle contraction. Cathinones can cause a range of other effects on human brain including lower inhibition, anxiety, and depression. It produces feelings of euphoria and empathy as well as increasing alertness and talkativeness.
CATHINONE USES
Some synthetic cathinones such as methylone has been found to be an antidepressant and antiparkinsonian agent. Few cathinones have not been exploited clinically because of their abuse and dependence potential. Diethylcathinone (amfepramone) is an appetite suppressant, which was used in the treatment of chronic fatigue, but later withdrawn due to dependency in users.
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RESEARCH USES OF CATHINONE
Synthetic cathinones are research chemicals that can be used to identify other effects of these drugs on human body so that better analogues are developed for treating serious conditions in humans. Researchers know that synthetic cathinones are chemically similar to amphetamines, cocaine, and MDMA, so they can use this drug in their scientific experiment to find more effective but less addictive drug for treating depression, schizophrenia and other mental conditions. Much of the current knowledge on health related effects comes from clinical observations. Further research is needed to provide evidence of health effects associated with the use of these substances. For such clinical studies and scientific experiment in laboratories, you can buy synthetic cathinones fromtrusted research chemicals supplier in Europe or in your native country after checking the legality of the drug in your location.Here
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